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Neuromedin N

CAS No. 92169-45-4

Neuromedin N( Neuromedin N (rat, mouse, porcine, canine) )

Catalog No. M29784 CAS No. 92169-45-4

Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Neuromedin N
  • Note
    Research use only, not for human use.
  • Brief Description
    Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.
  • Description
    Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.(In Vitro):Neuromedin N competitively inhibits the binding of neurotensin to rat brain synaptic membranes with a 19-fold lower potency than neurotensin and is rapidly inactivated by brain synaptic peptidases. It competitively inhibits neurotensin binding to rat brain synaptic membranes and has increased potency in the presence of the peptidase inhibitor bestatin.
  • In Vitro
    Neuromedin N competitively inhibits the binding of neurotensin to rat brain synaptic membranes with a 19-fold lower potency than neurotensin and is rapidly inactivated by brain synaptic peptidases. It competitively inhibits neurotensin binding to rat brain synaptic membranes and has increased potency in the presence of the peptidase inhibitor bestatin.
  • In Vivo
    ——
  • Synonyms
    Neuromedin N (rat, mouse, porcine, canine)
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Dopamine D2 receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    92169-45-4
  • Formula Weight
    745.95
  • Molecular Formula
    C38H63N7O8
  • Purity
    >98% (HPLC)
  • Solubility
    H2O : 50 mg/mL (67.03 mM; Need ultrasonic)
  • SMILES
    ——
  • Chemical Name
    Sequence:Lys-Ile-Pro-Tyr-Ile-Leu

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Li XM, et al. Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Neurosci Lett. 1993 Jun 11;155(2):121-4.
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